Neonatal invariant Vα24+ NKT lymphocytes are activated memory cells
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چکیده
منابع مشابه
Increased Intraepithelial Vα24 Invariant NKT Cells in the Celiac Duodenum
Celiac Disease (CD) is an interferon (IFN)γ-mediated duodenal hypersensitivity to wheat gluten occurring in genetically predisposed individuals. Gluten-free diet (GFD) leads to a complete remission of the disease. Vα24-restricted invariant NKT (iNKT) cells are important to maintain immune homeostasis in the gut mucosa because of their unique capacity to rapidly produce large quantities of both ...
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Vα24 invariant natural killer T (iNKT) cells are a subset of T lymphocytes implicated in the regulation of broad immune responses. They recognize lipid antigens presented by CD1d on antigen-presenting cells and induce both innate and adaptive immune responses, which enhance effective immunity against cancer. Conversely, reduced iNKT cell numbers and function have been observed in many patients ...
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ژورنال
عنوان ژورنال: European Journal of Immunology
سال: 2000
ISSN: 0014-2980,1521-4141
DOI: 10.1002/1521-4141(200006)30:6<1544::aid-immu1544>3.0.co;2-i